Obstetric cholestasis: symptoms, causes and which doctor to see
Obstetric cholestasis (intrahepatic cholestasis of pregnancy) is a rise in bile acids in the blood as bile flow slows, usually in the third trimester. Severe itching without a rash, especially on the palms and soles and worse at night, is typical. Because it carries risks for the baby, tests and close monitoring are needed; it goes away on its own after birth.
Which doctor should I see for obstetric cholestasis?
For obstetric cholestasis you can first see: Obstetrics & Gynecology. If you are not sure, a family doctor can refer you to the right specialist.
What are the symptoms of obstetric cholestasis?
- Severe itching without a rash
- Itching on the palms and soles that gets worse at night
- Dark urine and pale stools
- Rarely, jaundice
What causes obstetric cholestasis?
The most common causes are listed below. Only a doctor’s examination can determine the exact cause.
- 1Pregnancy hormones slowing the release of bile from the liver
- 2Genetic tendency
- 3Multiple pregnancy
- 4Cholestasis in a previous pregnancy
When is it an emergency? Call 112 now
- Has the baby been moving less
- Is there confusion, fainting or difficulty waking up
- Is there facial drooping, slurred speech or sudden weakness in an arm or leg
- Are you struggling to breathe even at rest
What you can do at home
- Tell your doctor about any new itching in pregnancy.
- Cool showers and cotton clothes bring relief.
- Track the baby’s movements every day.
See a doctor if
- The same day or within a few days when itching without a rash starts in pregnancy
- Immediately if the baby’s movements have reduced
How long does it last and how is it treated?
Treatment recommended by the doctor reduces itching; bile acids are monitored and the timing of birth can be planned accordingly. It clears within a few weeks after birth.
Who gets obstetric cholestasis?
- Women in the third trimester
- Women expecting twins
- Women who had cholestasis in a previous pregnancy
How is it diagnosed?
It is diagnosed with blood bile acid and liver tests.
Can it be prevented?
- It cannot be prevented; early diagnosis is important.
Find a gynecologist in your city
Gynecologists in Turkish cities who can help with obstetric cholestasis.
People also describe it as
- “I am pregnant and my palms are itching like crazy”
Frequently asked questions
Which doctor should I see for obstetric cholestasis?
For obstetric cholestasis you can first see: Obstetrics & Gynecology. If you are not sure, a family doctor (general practitioner) can assess you first and refer you to the right specialist.
What are the symptoms of obstetric cholestasis?
Common symptoms: severe itching without a rash; itching on the palms and soles that gets worse at night; dark urine and pale stools; rarely, jaundice. Symptoms vary from person to person; a doctor’s examination is needed for a diagnosis.
What causes obstetric cholestasis?
The most common causes: pregnancy hormones slowing the release of bile from the liver; genetic tendency; multiple pregnancy; cholestasis in a previous pregnancy. Only a doctor’s examination can determine the exact cause.
How long does obstetric cholestasis last and how is it treated?
Treatment recommended by the doctor reduces itching; bile acids are monitored and the timing of birth can be planned accordingly. It clears within a few weeks after birth.
Who gets obstetric cholestasis?
It is more common in: women in the third trimester; women expecting twins; women who had cholestasis in a previous pregnancy.
How is obstetric cholestasis diagnosed?
It is diagnosed with blood bile acid and liver tests.
Can obstetric cholestasis be prevented?
It cannot be prevented; early diagnosis is important.
Is itching normal in pregnancy?
Mild itching from the stretching skin on the abdomen can occur; severe itching on the palms and soles should be checked for cholestasis.
Can obstetric cholestasis harm the baby?
It can raise the risk of preterm birth and other problems; so close monitoring is needed.
When is obstetric cholestasis an emergency?
If the answer to any of these questions is yes, call 112 without delay: “Has the baby been moving less?” “Is there confusion, fainting or difficulty waking up?” “Is there facial drooping, slurred speech or sudden weakness in an arm or leg?” “Are you struggling to breathe even at rest?”
When should I see a doctor for obstetric cholestasis?
See a doctor: the same day or within a few days when itching without a rash starts in pregnancy; immediately if the baby’s movements have reduced.
Similar complaints
Emergency numbers in Turkey
112: ambulance, emergency (free, 24/7, from any phone). 114: National Poison Information Centre. 182: appointment line for public hospitals (MHRS). Pharmacies on night duty (nöbetçi eczane) are posted on the door of every pharmacy.
Sources
This page is based on current information published by the official and independent bodies below and on our editorial principles. Last updated: . To report an error: contact us.
This page does not provide a medical diagnosis and does not replace an examination by a doctor. If you think it is an emergency, call 112 (Turkey’s free emergency number). For poisoning, call the National Poison Information Centre on 114.








